Tsunade:
While a medical-nin normally tries to avoid direct battle, Tsunade's taijutsu has been considered unsurpassed, which she uses mainly to intimidate her opponents from approaching her in order to carry out her primary duties as a medical-nin
While not her most prominent trait, she is quite fast and equally fierce in battle, having displayed high levels of quickness to the point that her opponents find her an overwhelming adversary. She was able to incapacitate Shizune with a quick strike before she could react,[31] use the Body Pathway Derangement technique on Kabuto when he thought she was incapacitated, use her feet to counter Orochimaru's sword moments after her hands were bound, and even intercept Manda mid-bite while lifting Gamabunta's sword. Before any of the other Kage could react, Tsunade intercepted all five of Madara's flame dragons dissipating them all.[32] As a field medical-nin, Tsunade is highly skilled in the art of evasion.
Sakura:
Sakura's taijutsu skills have seen tremendous growth thanks to Tsunade's training.
Another key component of Sakura's fighting style is her evasive skill. As a field medic, she cannot afford to be gravely injured or killed on the battle field, as drilled into her by Tsunade when she trained her. Sakura would attempt to read an opponent's fighting style in order to find the dominant hand/foot or anything that the enemy was using. With that, she could increase her evasive skill to impressive levels. Sakura was proficient enough in this that she could figure out Sasori's finger movements and predict the movements of his puppets. Sakura's skill in evasion is so great that she can completely evade a barrage of poisoned senbon, a multitude of puppet arms, and defeat one hundred puppets without even being scratched.