I wanna talk about how kishimoto has completely destroyed the naruto manga beyond any restoration.
Many of the things you mention are based around various Japanese/Chinese lore/legends (particularly Shinto concepts expressed by the Sharingan, Buddhist by the Rinnegan, and Taoist by the Byakugan). Izanagi and Izanami were brother and sister, respectively. Izanami 'died' and took up residence in the underworld (the Edo world). Izanagi went to retrieve her - finding her to have embraced her life in the underworld (and horrified by her appearance, which was no longer that of a 'living' person). He fled the underworld as she chased after him, attempting to seal him in with her. He escaped.
Honestly, I think his implementation of Izanagi was alright. It's an ability where one flees from death. Izanami, however, was poorly implemented and very horribly explained (apparently, Izanagi was a spammable technique back in the day... because the fact it would make people go blind was obviously not enough to keep them from using it all the time).
Susano'o, Ameterasu, and Tsukuyomi each play into the same legend.
The DNA stuff is a little out there... but it's no worse than super hero comics. "I got hit by some toxic waste and now I can shoot glow-beams out of my eyes!"
That, and the list of authors who have a solid-enough grasp of DNA/biochemistry to write a convincing plot around it are pretty rare. Not that much of the reader base would grasp the concepts. Most would literally argue: "That's bogus! We can get each others DNA by kissing. The author just likes using fancy words and equipment."