I'm assuming that Madara has Hashirama's Sage Mode here, since this isn't debatable otherwise due to Onmyoton.
With Juubidama restricted, Obito has no actual way to bypass Perfect Susanoo's defense, especially since its been enhanced with Senjutsu, making it stronger, and making it immune to Onmyoton's effect to negate all Ninjutsu. With the Shinju restricted, he can't absorb Perfect Susanoo either, so that is out of the question. That leaves Obito with the jutsu he had before becoming the Jin (worthless here) and the Gudo Dama. The Gudo Dama are strong enough to tank things like a Senjutsu enhanced Bijuu Dama from Naruto, albeit with damage. PS enhanced with Senjutsu should be enough to get past the Gudo Dama shields, and they are definitely enough to kill Obito if a direct hit lands. Obito isn't going to effortlessly evade his attacks either since EMS Sasuke had the reactions and precognition necessary to tag Juubito with his V3 Senjutsu Susanoo. Madara should be able to replicate the same thing since he has EMS, the same straight tomoe as Sasuke that gives him the best precognition, Senjutsu to increase the speed and strength of his Susanoo and Sage Mode to enhance his natural reflexes, something Sasuke lacked in his bout with Obito.
Madara would probably take it.