Totsuka probably doesn't possess enough power to seal Juubi's host. If he wasn't jinc, probably it could but he might resist with his Susano'o and dojutsu as well. Someone on Madara's caliber cannot be sealed easily.
To bad he got killed by a disease (whyy??) But why did he undo the Edo Tensie if his Totsuka Blade can seal anything but if he did that the kages would be dead when he got there and good look piercing Perfect Susanoo
No it sealed Orochimaru but Sasuke figured out how to get one from a curse mark therefore if Madara is sealed someone probably couldn't get a new one because he doesn't but curse marks on people.