Naruto takes this:
1. Itachi has low chakra reserves.
2. He only has MS so he can't spam his Susanoo or MS techs in general like he could as an Edo.
3. Even if the above wasn't true, Naruto has Kurama to get him out of any genjutsu and he has the TBB.
4. Naruto has unbelievable speeds and mountain busting attacks.