Asuma is Ino's teacher, so she likely wouldn't be able to trick him and use the Mind Transfer. She'd be wiped out by Asuma pretty quickly
Konohamaru will likely be pretty useless also. He has been shown to have some talent and will probably become powerful in the future, but ATM, he won't be able to handle Mokuton, even if it is from Zetsu.
So, it would pretty much be a fight between Zetsu and Asuma, which I think could go either way. If Zetsu is able to keep his distance and attack from there with Mokuton, he might take this, but if Asuma manages to get close enough to hit him with any of his fire techs or chakra blades, Zetsu is done for.
IMO, it's pretty much a 50/50 fight, it could go either way. People are really underestimating the Z-man