If Sakura gets her head cut off. . . ?

[Xāvî1]

She will die!!

 

[hitrho5]

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[TenthHokagexRamen]

die. All the chakra is stored in her forehead thus detach her head and it's over.

 

[Antichrist]

The proof lies within your brain. Gotta look deep under those neural tissues of stupidity.

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[Awkward Linguist]

She grows a new body, until proven she can't. She can regenerate. Her chakra is in her head.
Madara grew legs

According to your explanation, Tsunade should have regenerated legs when she was soloed by a tree. Also, you should know that there is a difference between Madara's/Hashirama's regenerative ability and Tsunade's. If you're up to date with the manga, this should have been apparent.

 

[KillerbYo]

If she gets her head cut off she dies, Naruto cant bring people back from dying.

 

[Awkward Linguist]

She's more useful with her head cut off.

 

[Your Creepy Stalker]

Then people would cheer.

Unfortunately, she would probalby regenerate.

 

[Jack Spicer]

You are all stupid.