I would understand it more if it was the same 'curse of hatred' that floats around every ninja in the Shinobi world as they have to battle against hatred like Minato said. But the fact that the Uchiha curse of hatred itself is a curse passed down simply through genetics by being linked in heritage with the Juubi, I don't see how Sasuke will be able to permanently stop that from occurring through morals. All the offspring that he will produce will still have that genetic disorder passed down.