How do i encrypt/password my harddrive

[Luther]

I have a transcend hard drive that is about 500gb or so how do i password or encrypt it in a way that no one can view it without a password and that it would not cause any error on the hard drive.​

 

[Kraminka]

I'm not sure about a whole HDD, but you can encrypt folders:

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So, if you had all of your subfolders inside one folder, you could encrypt that.