Sasuke wins this mid-high difficulty.
Sasuke has been
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at the kage summit and now he can even keep up with Juubito's movements. Whereas part 1 Kabuto managed to outmaneuvre Tsunade plenty of times(
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)(
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)(
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). Yes Tsunade is faster and more agile in Shippuden considering she had a
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before her part one fight, but my point still stands as Sasuke has demonstrated countless shunshin blitzes (
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)(
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)(
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) whereas Tsunade only managed to catch her opponents off guard when they were
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or
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.
As for how Sasuke ends Tsunade, well his
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can extend at least 5 meters whereas Tsunade has to come within 1 meter to punch Sasuke so Tsunade's fighting style puts her at risk of getting decapitated by chidori sharp spear which it can since it managed to slice a tentacle off the Hachibi with ease.
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as what has already happened in the manga and even still, Katsuyu can't risk attacking Sasuke with acid when Tsunade will most likely, due to being a CQC fighter, be close to Sasuke.
The location is Sasuke VS Deidara so there is a
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. These trees can help Sasuke take cover from acid and allows Sasuke to
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to avoid Tsunade and potentially
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.
As for Tsunade's shockwaves. Sasuke has many counters which include wrapping up his body with snakes to take the impact of those shockwaves. Another way to defend himself are his
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from Deidara.
I haven't even talked about Sasuke's genjutsu which would temporarily paralyse Tsunade or giant raiton enhanced shuriken. I guess it would be a mid difficulty victory.
