i think tobirama and hashirama,if its 1 vs 1, can handle any other kage(non hokage), so lets say tobirama vs 4th and hashirama vs 3rd....for me hokages wins
no restriction, full knowledge, tobirama CAN do edo tensei and both senju bros can do ultimate darkness genjutsu(cos in anime tobi did it, however in manga hashi did it)
no restriction, full knowledge, tobirama CAN do edo tensei and both senju bros can do ultimate darkness genjutsu(cos in anime tobi did it, however in manga hashi did it)
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