Nope. Not much would be different from their last fight. Rinnegan Obito's strength lies in his Jins. Without them.. eh.
So what if Tobirama was sure he could kill Sasuke? That means nothing as he knows nothing about the guy he was about to face.
He saw his MS, knew he's an Uchiha. He clearly wasn't impressed by it. Not only that, he's a sensor, so he can feel how strong someone's chakra is.
The only person he seemed worried about was Madara and it's well known Sasuke is nowhere near Madara.
ince Obito and Itachi's battles will be over quicker than Madara and Hashirama's.
Hashirama's Shinsuusenju covers the whole battlefield. No way in hell anyone else but Madara can hope to live against that thing.
Match ups don't mean shi t when someone has access to a technique of such a big scale as the Shinsuusenju.
That, and Flower World, which puts them to sleep.
If anything, I'd dare say it's Madara that is dragged down. Minato can simply tag everyone and port them on top of Shinsuusenju, and there's nothing a Susanoo which is 1/100 of its size can do.
