Last one I played was Brotherhood.
I always had this head-canon/what-if? that Ezio or an assassin would visit Spain, confront the Inquisition, use (or get used by)
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and find a piece of Eden in the Fountain of Youth. Maybe fighting against Juan Ponce de Leon (the conquistador who tried searching for the Fountain in Youth)
Maybe he didn't find it because he was assassinated? lol
All these events occurred during the 15-16th century.
Lynch discovers he is a descendant of the secret Assassins society through unlocked genetic memories that allow him to relive the adventures of his ancestor, Aguilar, in 15th Century Spain. After gaining incredible knowledge and skills he’s poised to take on the oppressive Knights Templar in the present day.
It's happening?