i think first hokage will fight madara for round 2 or kishimoto might resurrect another person if he didn't then all rest upon the 2,3,4 hokages to save them
tsunade can't stand against madara naruto can't do a thing either what do you think mashashi would do to erase madar existence.don't tell me he is going to use naruto to talk him out of it like he did to obito