Kid please, Itachi outbrains the entire Narutoverse, your ''counter'' theory for Totsuka and Yata is absolutely BULLSHIT.
You and all the other Itachi haters are just BUTTHURT because Itachi is invincible (as stated in the manga) He was too strong so the only possible way to kill him was to give him a disease because NO ONE would have been strong enough nor would they have the brains to kill Itachi.
But you also seem to forget that Itachi owned the shit out of some well respected and skilled Shinobi IN JUST SECONDS WITHOUT ANY EFFORT WHILE HE WAS SICK and trying to pro-long his life with medicine...
He never lost a fight and that wasn't even prime nor healthy Itachi.
Just deal with it Kiddo's
ITACHI SOLO'S THE NARUTOVERSE
Itachi > You and your BUTTHURTNESS.