The fact that THAT Sasuke was still injured and recovering from his fight with Itachi paints a different picture - confirmed by Jugo and Sasuke's dialogue exchange. His bodily reflexes were obviously NOT up to the mark. It's a very real biological fact. The same Sasuke dodged V1 Ae's speed Blitz - and Bee's as well - without breaking a sweat. He only couldn't keep up with V2 Ae's Armour, which he had incidentally juiced with Bijuu level Chakra. His eyes could still keep track, as he saw his movement and erected defenses. Get your facts straight.
As for the thread, then Sasuke wins with ease. Tobirama is not faster than Sasuke as far as foot speed goes, hence there is no way in hell he is marking him that is for sure. He's electrocuted with Raiton Variants and Enton Sword fires him. This is such an easy win that it's not even funny.