V2 is a bit much for itachi to handle, considering he's immune to genjutsu which is itachi's bread and butter, and has ridiculous speed and strength. Gaara is also an amazing counter for susanoo, being able to yank him out by the feet and block ameterasu with sand. On the other hand, neither of them have sealing techs.
apparently kabuto had sasuke not been there\Edo Itachi is one of the strongest characters in the manga, has unlimited One shot techniques, seals everything and needs to be sealed to be defeated. I dont know what could take care of him.
how does totsuka get past the shroudbee gets sealed
bee gets sealed and then gaarra stomped with amaturasu, over