None of these guys have anything that can put him down.
Madara uses the Wood Dragon to bind Itachi's Susanoo which proceeds to absorb Itachi's Susanoo since it's chakra.
He uses Jukai Kotan to finish off Sasuke and Kakashi, though Sasuke might survive due to Susanoo, if he does Madara uses the Flower Tree World and he gets put to sleep, where Madara then kills him with Mokuton.
After Kakashi and Sasuke are dead, Madara returns to Itachi and rips his soul out.
This isn't an epic fight; it's completely one sided in Madara's favour. He has Rinnegan, and EMS, and you've also added infinite chakra and an immortal body into the equation. Take out Edos on both ends, and it's still Madara's win due to an additional arsenal of kaleidoscope techniques, namely the 7 paths. Madara wins this Edo or without it (by nullifying Edo on both sides) without any difficulty whatsoever.