prime sasuke, when?
anyway, sasuke has a good chance of winning if he shows the ability to materialize the two spiritual weapons in his susano'o. if he does have it, this is how he defeats madara: massive kirin + after kirin subsides, the powerful after blast would create massive smoke in the vicinity of the area lowering detection rate + instant amaterasu that targets the enemy (madara's) eye, hindering him from using anymore of his doujutsu and quite possibly blinding him in the process + troll him with a totsuka blitz. madara's arsenal of attacks is easily nulled by simply guarding with the mirror.