Maybe, maybe not. I honestly don't care unless she remains Hokage after this and there's a new arc about them after the war, preferably 1-2 years later. I don't want to see them so old.
Orochimaru will watch as she dies and finally realize, like sasuke, the error of his ways. Because then he will be the last of the three Sannin, everyone who might of meant something to him is dead, besides sasuke. His pupil.
Personally i think she will die and naruto and sasuke will fight it out to replace her once the war is done. (off topic) I'm also kinda wondering if naruto or sasuke might die in the big battle. like picture Naruto dieing to save sasuke and then sasuke upholds narutos dream for peace as hokage of the leaf or somethin like that