It’s been evidenced that Sakura can’t take blunt force to the head, as shown when Kabuto’s butt knocked her out cold simply by knocking her head against the bridge. The Hyuga could replicate this with her Air Palm, easily blitzing her with it, mind you.
Neji’s basic Air Palm provided enough force from about 4 M away to send someone as heavy as Kisame flying, and he would not have stopped had he not had Samehada with him. Now image a Hiashi or Hinata's Air Palm being used on a much lighter opponent who has nothing to help stop her body from flying. results would be more devastating than what either did to the Juubi’s hand
Thus, I conclude that an Air Palm to Sakura’s body will send her flying and knock her head on a wall, thus it will render her unconscious, ergo leaving only Tsunade
People love to claim that Sakura is a tank when it’s the exact opposite lol