Did Tsunade Actually Tank Pain's Shinra tensei on the leaf?

[Horus]

Yep, she faced it head on, because she was running towards Pain when he used it. She has not Katsuyu Support, as all the clones were scattered around every villager.
Yet she was able to Outrun an Anbu!
She has an extremely strong Durability, so she can tank most things, being senju and Uzumaki