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No... She regenerates at a cellular level. All rgeneration takes place at a cellular level. No cells means no regen, no dna means nothing to copy. She wouldnt exist as molecules.
Fire? clay is made of water and earth and an explosion isnt just fire, its 2 or more things splitting appart. No fire needed.
Well yeah but if she regenerates at cellular level, in order to damage everything it has to pass from the cellules, right?
And if they keep regenerating, how can she die? I mean, every injury that she receives heals instantly.
As for the clay, well, Mei has 2 kekke genkai. So, somehow I think she could counter his explosion. Meaning she could either melt it with lava or with her corrosive mist...