I don't think its possible to use izanagi if your soul is taken away .-.True, the user would die, however Sasuke could use Izanagi, so that would be avoidable ? :hooray:
Maybe I'm just imagining things, haha. But seen as Madara used it, I think Sasuke could do that either ;xI don't think its possible to use izanagi if your soul is taken away .-.