Well Tsunade without healing abilities is significantly nerfed and without them, I don't even think she is kage level. She still has Katsuyu, raw physical strength and good taijutsu so it shouldn't be a stomp. You gave Darui full knowledge so he can just use black lightning and kill Tsunade with it. Tsunade won't be able to close the distance between them without regeneration. She could use Katsuyu for some long range fire power so she does have a pretty good chance at victory but Darui should be able to dodge the acid.
Darui wins high difficulty.