Compared it what sense? Relative to other ninja all of them are in the top 1%. So in that sense they can be compared.
Now, in relavence to the shinobi world can the three shinobi above be compared?
Yes, they are all top teir and famous.
If we are talking about comparing in a general sense
Jiriaya- ( teacher) taught some of the worlds most powerful ninja and gave them his will
Tsunade- (doctor) revolutionized the medical world, her medical prowess played a large role in the 2nd shinobi world war
Orochimaru- ( Scientist) found a way to become immortal, great understanding of natural world ( his servent could splice dna of different people) -so orochimaru probably can.
Hiruzen-( Hogake)- noted to be strongest kage of his time, ruled konoha for many years.
Can they be compared to each other off achievemnts?
No, successfull doctors, teachers, scientist, or leagers are too differnt to be comparable in any way.
If we are talking about achieving their dreams
-Jiriaya- find piece, a world were people understand each other- not realistic but considering the way the manga is going Jiriaya's student is going to fullfil his dream.
Orochimaru- In part 1 he wanted to "obtain all justu", however now his motivations are not known. If you consider his immortal status, and if you consider his edo tesnei's justu as part of his power, then Orochimaru is getting there.
tsunade-Not sure about her goal? Marry dan? Promote Naruto to hogake? gamble?
Can they be compared on fullfilling their dreams?
No, tsunade's dream was crushed when dan died and we don't know if she has a new one. Jiriaya is dead, however his dream lives on in his student, surprisngly, Orochimaru is the closest to achieving his goal out of the sannin.
I didnot include hiruzen because the naruto story doesnot realy involve him in the "main" plot. We don't know enough about him to compare him to the three sanin.
We can only compare him in the first point.