first you andwer
1- are they also Edo...? if yes
then hell yeah they will the beat crap out of him cause itachi will his totsuka blade n kisame insane strength n the pain rinnegan abilities are nothing to be taken lightly
2- if no
eventually madara will own them but ITachi kisame pain and all will definately give 6POP, Konan, Itachi, Kisame, Kakuzu, Hidan, Sasori, Deidara. will atleast put better fight then THOS FIVE KAGES
Even Itachi and Pain are fodder before the perfect Susanoo. The rest of Akatsuki is nothing compared to it, the 5 Kage were also nothing compared to it.
If Madara has sufficient Hashirama DNA, he can create mokuton clones that will give him the chance of winning along with perfect susano. Otherwise, it's really hard and it might come to the point that Madara gets gang-raped by Akatsuki xd
Edo Madara or EMS Madara? Either way perfect susanoo is a last resort move by Madara and he will most definetely have to rely on it against the sheer number of Akatsuki members.
Also keep in mind that samehada absorbs chakra and susanoo is a physical manifestation of the user's chakra so it can be absorbed or at least destabilized or weakened.