Did we forget that Orochimaru was controlling Hashirama? Orochimaru didn't know what to do with the two powerful Kage. But Hiruzen is strong and I bet in his prime, he could solo anyone, even Madara.
Naruto is going to change Sasuke. Did you guys think he was lying when he said it 99.9% throughout the series? He's willing to die for his brother Sasuke!