DO you mean regular Madara or Edo Tensei Madara. Edo Tensei Madara would beat Hashirama by himself. Hashirama could barely beat Madara without the Rinnegan and wood style.
Oh, all the Akatsuki ? Yes.
If your're going about all the Akatsukin members against Hashirama, you might as well ad Naruto for back up.
So I say Hashirama/Naruto > The akatsuki deceased and living.
Yet he was only tired by the end of the fight ^_^. But he will loose this fight though X)XHashirama had trouble taking on madara by his own, against the others i think he will lose
If you look at the manga showing Hashi vs Mada fight, Hashi was pretty messed up. Akatsuki could kill him.