Sakura, under the impression that Sasuke came back, she waits for that so-called kiss and we witness one of her biggest change from a bratty teen that is quite superficial and mainly talks before she thinks.
When Sakura says that he (Naruto) doesn’t even have any parents demonstrates how superficial in thinking she is. But for a 12 years-old that has had her parents all along and doesn’t know how it is to grow-up without a parent, it is normal to be shallow in thinking. All she thinks about is the fact that Naruto doesn’t have to worry about getting late home because he has no parents to scold him. That was her incentive, not that she’s a total bitch and he laughed about him not having parents.
I mean, let’s be serious, how many of us didn’t think at early ages of our childhood, we wish we were alone with no parent to scold us, not that we wish for our parents to be dead – GOD FORBID! (I felt I had to specify this as I am sure some of you would get crazy over this statement and interpret it in the wrong way

) - but just not be there so we can do whatever we wanted without fearing that later we’re going to be scolded for what we did. If you say you didn’t, I’ll have to call you a hypocrite, sorry. There’s no youngster that doesn’t think like that when parents don’t let us do what we want. So basically it’s the same premise here.
That was the message behind the curtain. But it seems like many didn’t understand it and started bitching about her, ALTHOUGH, in the next panel, given Sasuke’s rebuke, Sakura realizes the fact that she did wrong and this would hurt Naruto’s feelings and asks herself if Naruto felt the same way she did after Sasuke’s acted the same way she acts to Naruto and says to herself that next time she could be a little nicer to him.
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So there we have, the 12 years-old shallow Sakura, acknowledging the mistake she did and thinking about changing her behavior towards her team-mate in order not to hurt his feelings as she saw on her own skin how it is to be hurt.
A majorly overlooked aspect of Sakura’s character.
But of course, why praise her for that, when we can still bash?