Kakashi solo's with Kamui.
LOL, no not going to be that guy.
But yeah I think team 2 take this, but it certainly wouldn't be easy.
We don't know a lot but based on what we know Tobirama has a s/t technique which from the way Minato talks about it is teleporting, probably somewhat similar to Obito's but not as fast and not going in to another dimension.
So we can assume he can dodge fairly well.
Tobirama could get away from Kamui with s/t. Kakashi's is nowhere near as fast as Obito's which Minato got away from, it's easy to tell when Kakashi is using it on you(see Deidara fight) you feel your body warping so Tobirama could teleport away from that.
He also has Edo Tensei.
Unknown who he can revive but presumably he would revive Uchiha clan members to fight against them rather than disgrace his own clan.
His Suiton is apparently unmatched(say what you want about Kisame but he needs water or Samehada to be good)
one of them able to match him in Suitonjutsu (or at least nearly)
^What? I assume you mean Kakashi? Water Wall isn't that good that's basically all he has, I doubt water is a good defense against water and Water Dragon has yet to be that good.
Other than healing Tsunade wouldn't be that useful in this fight...
I think team 2 would win mainly because Kakashi and Gai are just an epic duo and would overwhelm Tobirama, but it would be close.