Itachi is more skilled in terms of genjutsu, however, a 3 tomo Sasuke broke out of Tsukiyomi (I know, the fight wasn't necessarily Itachi at his hardest, but we can also assume that Sasuke has gotten a lot stronger since then). Thus, we can assume that genjutsu won't be an issue, and would just be a precursor to the real fight.
Next I'll talk about Susanoo. Susanoo vs Susanoo would be interesting I'm sure. Sasuke's would certainly be unable to break through Itachi's (Yata Mirror), but would Itachi's be able to break Sasuke's? The Sword of Totsuka cannot seal non-living things, and Sasuke's Susanoo is just chakra...It may be able to withstand a blow. I think here, Itachi has the upper hand, but I personally believe he still wouldn't be able to break Sasuke's Susanoo without losing most of his Stamina.
Amaterasu is in favor of Sasuke, but once again it's another stalemate overall. Both are capable of putting out the flames, so they will only mimimally damage either of them, maybe Itachi a little more.
Stamina is in clear favor of Sasuke. If in the battle all of the above happen, and they all stalemate like I suggest, then Sasuke comes out on top.
Intelligence is important, but not everything. Yes Itachi has the edge, but when he tries, Sasuke can be an incredibly shrewd fighter as well. I think they are both almost even in battle smarts (when they're actually trying to be smart, NOT the Kage Summit). Itachi has the slight edge, but not enough to give the win to him over Sasuke's stamina.
Izanami I have explained in a previous thread would be almost impossible for Itachi to activate, it should hardly be considered at all.
Also, these are just the main attacks. Sasuke is also far more dominant in ninjutsu variety and power, and all of that would serve to weaken Itachi further, widening the already large stamina gap.