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the reason is that the sage had the ten tails so madara could still be showing the base form
the uchiha were already one with the senju unlike kakashi who is not related to the sage,the uchiha and senju were once one before so they are compatible if you inserted the dna in them.
edo madaara has infinite chakra and regeneration so they are close or since madara can regenerate he could be considered to have a body advantage.
Human being originated from a single source then shldnt that count too? They may be compatible but a few cells does not carry the full power of person no matter what way u look at it.
Also an Edo does not count as a fair match up . . . . If Sage was brought up as an Edo he wld be stronger than anything.