I don't think you need senju because danzo used izinagi a good plenty of times but I might be wrong I think he didn't have senju
I think uchihas dont need senju dna it's just for non uchihas that's why Tobi and Danzo need it.
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Read this scan These are Itachis words it seems to me that more then 1 uchiha was useing izanagi and izanami was created to punish the users. Why would the uchiha develop a costly genjutsu to punish izanagi users if only the ones who have senju DNA can use it?
Itachi claims that Izanami was created to punish and teach the Uchiha's who at certain point in history were abusing of the powers of Izanagi. On the other hand Tobi said that only those who possess both Uchiha and Senju's powers can use Izanagi. Either this is a plot whole or it means that Uchiha Madara did nothing original by sicking to gain access to Senju's DNA.
Maybe, just maybe this might shed some light onto who Tobi might be. Uchiha older than Madara? Your thoughts.
What if he is a senju with a sharingan implanted:shrug:
What if you dont need Senju dna to use Izanagi![]()