I know alot of people don't agree, but i have a feeling and a hope that Tsunade will stay alive, simply because i don't think Naruto is old enough or more importantly, mature enough to take on the responsibilities of being Hokage. Do you really think Naruto will become Hokage before Minato? Also Naruto may have some crazy power, but he doesn't actually have that many Jutsu. Kage Bushin, Rasengan, Rasen-shuriken, Sage mode and the 9 tails. He hasn't technically mastered a single element and Jonin level shinobi normally have two elements down. Naruto needs to have some more training before he can become Kage and needs to acquire a greater knowledge of the Shinobi World.