Kakashi wins.
Without Tsukyomi, Amaterasu, and Susanoo Itachi has nothing and wouldn't be so confident in a fight against Kakashi or any shinobi on a high level.
Without Sharingan Orochimaru would have wiped the floor with Itachi.
Without Sharingan Deidara would have killed Itachi.
Without Sharingan Itachi would not have escaped Jiraiya.
Without Sharingan Itachi would not have killed a single Uchiha.
Without Sharingan Itachi would be at the bottom of Akatsuki organization, if in it at all.
Itachi would be no more powerful than Sakura or Kiba without his precious Sharingan.
Kakashi was a child prodigy before implanting the Sharingan.
Kakashi graduated from the academy at age 5 before getting the Sharingan.
Kakashi became chunin at age 6 before getting the Sharingan.
Kakashi became Jounin leader at age 12-13 before getting the Sharingan.
Kakashi invented his own original jutsu(Raikiri) before getting the Sharingan.
Kakashi could use advanced lightning jutsus before getting the Sharingan.
Kakashi could use proficient water jutsus without use of the Sharingan.
Kakashi could use proficient earth jutsus without use of the Sharingan.
Kakashi could use proficient fire(Anime) jutsus without use of the Sharingan.
Kakashi was well versed in all forms of ninja combat before getting the Sharingan.
Kakashi had heightened senses of smell and hearing well before getting the Sharingan.
Kakashi is extremely fast without the use of the Sharingan.
Kakashi was a genius before getting the Sharingan.
Kakashi still has a wide array of jutsu without the Sharingan.
Kakashi would still know 1000 jutsu without the Sharingan(Since the Sharingan doesn't automatically grant you a jutsu you've seen, you still have to learn it and practice it, it would have just taken Kakashi longer to do so).
Kakashi without Sharingan would obliterate any Uchiha living or dead without their Sharingan's.