Yes. He has more stamina and can outlast Itachi. He also won't suffer from eye damage from using the mangekyo sharingan. His taijutsu is probably better. The only area he loses in is genjutsu. If Itachi used tsukuyomi then he might fry Sasuke's brain. Itachi also has yata mirror which will render all of itachis techniques useless. It'll be a battle of substitutions, deception, and illusions because if either one of them get hit by amaterasu then it's over. That will force both of them into their complete susanoo modes. Itachi will win the susanoo fight.
Overall Sasuke loses to susanoo and tsukuyomi and itachi is smarter and more deceptive.