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Then every Hokage would defeat him, healthy or not.
Everyone except Kakashi
His most powerful weapon is his brain and his knowledge.
His most powerful weapon is his brain and his knowledge.

Are you talking about in a fight or something else?
The only way other people can defeat him is if you restrict him.
His base skills would give the Hokage a good fight tbh. His Shuriken ninjutsu is so good that he hit the King of Hell with the Rinnegan with his Shuriken.
His most powerful weapon is his brain and his knowledge.
KB in a nutshell
KB had to be told a genjutsu was coming for him to even react. Itachi's movements are slick. Itachi's Katon Shuriken burnt his hand pretty badly.
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Restricting him to his lowest potential is the only possible way to beat him.
lol nvm, for whatever reason i thought this thread said sasuke not itachi.
Itachi's greatest abilities are his genjutsu, so...
Uhh, you were still right though. Both brothers fought KB. Itachi was restricted in a way that he wanted to break out of Edo Tensei as fast as possible and not harm Bee and Sasuke's scenario is pretty obvious.
Dude came in with all sorts of injuries from his previous fight and Amaterasu wasn't used at critical moments. Where was the Shadow Shuriken technique that worked against Itachi? Thins like that.
yup. if you think about it, he pretty much fought an injured hebi sasuke without curse mark or orochi for most of their CQC.
OP: why restrict itachi to his amaterasu only? it's not even his best MS tech.