None of the above. Tobirama stomps all.
Maaaaaybe EMS Sasuke with PS, but most of Tobirama's techniques are perfect counters for Uchiha in general and Sasuke's moves.
Water Style > Fire Style. Gg blaze release and Katon: Great Dragon Fire Technique
FTG > Most of Sasuke's arsenal. Can evade Chidori, Sunsano Sword, Arrows, and Amaterasu/Enton because these attacks aren't instant.
Gojou Kibakufuda to the back of Susano peels it away, and even using the water at Susano's feet to extract Sasuke from the Susano could work too, similar to what Gaara did to EMS Madara.
Tobirama's sensory abilities allow him to see lots of attacks coming, forget about landing a sneaky Chidori.
Tobirama is a thorough bred anti-uchiha shinobi who is used to seeing the sharingan's arsenal. It's not really a case of Tobirama's raw power being greater than Sasuke's, it's just that Tobirama's abilities are super effective against everything Sasuke has, except maybe Kirin. Since Kirin is "Instant" (according to Sasuke when he fought Itachi), that jutsu could end it pretty quickly.