Sasuke - The sole reason why I have even stuck around with this horrendous manga.
Itachi - Never liked this patriotic nut-job. I dislike single-minded people who adhere to such National ethos with passion. He took KA eye from shisui and did nothing with it to quell the flames of rising tensions between Uchiha Clan and the political establishment.
Obito - He was awesome, until he compared himself to Naruto. Now all I feel towards him is an annoyed indifference.
Madara - He had a lot of potential, great back story, but his subsequent turn to Infinite Tsukuyomi was rushed in the flash backs. Still, I do like him.
Shisui - Not a likable character. In fact, quite supremely stupid, this fella. In lieu of taking matters into his own hands by utilizing his KAs, he loses it to Danzo, when he could have used it on him to completely end this whole matter. Another jingoistic loon like Itachi.
Kagame - Tobirama's private lap-dog. Man, I loathe characters - and people in real life - who back stab their own families.
Izuna - He has more character development then Itachi, Kagame, and Shisui combined, as we see how he loved his brother and fought along side him. I like this guy.
I like Uchiha Clan not mostly because of the characters, but because of the metaphorical connotations associated with their abilities. Amaterasu alone, borrows several religious layers in regards to hell, tears of blood, and Japanese Mythos itself. I have always found Amaterasu to be a wonderfully amazing technique in this regard - the best the manga has to offer to add complexity to the character, Clan, and story in general. it's a shame, I cannot say the same for other clans or characters.