I'm not sure if Hashirama can still take Madara on. However, it is hilarious how Kishimoto can make people believe that Madara appears to be even more powerful than Juubi Obito which is false and thus resulting in people overrating Madara as usual. Obito talked more than he fought, Madara does the opposite and that is why it appears that Madara is stronger, he's more dangerous but not stronger. Also, this is the same reason why people ignore the fact that Hashirama and Tobirama are both Edo Tensei's which means they are weaker, not to mention Orochimaru couldn't summon them at full power which was confirmed by Tobirama. While it is true that Madara became alot stronger, alive Hashirama is still in his league.
You guys had a fapfest when Madara became alive, saying how he's OP now and all that while a year ago Edo Madara was getting wanked; people stating how Edo Madara > Hashirama.
Edo Hashirama > Edo Madara
Alive Hashirama ?? alive Madara
I'd say it is still unknown so far, I think Madara might have more chance to get this fight, but definitly not easy.