It doesn't look real, it looks like someone edited the photo especially in the panel above the fanart. It's clearly not blended around her head and you can see someone layered this on to another image. And look at the scythe by her feet, it's jagged like it was rendered manually. It looks like someone rendered a fanart and placed it on top of an image. Also rukia's eyes are way off in that same panel, kubo draws eyes in a distinctive manner in every panel that I've noticed since I've been following bleach. Those eyes are not kubo eyes.
Also not to mention some of the characters in the scan aren't even japanese. Like for instance the first panel and the panel with ichigo aren't japanese characters in the speech bubbles.
This is fake but doesn't mean the idea is invalid. Anything is possible