It depends on who she is. If she is not that close to you, and her intent is to severely hurt you, then avoid her until it is no longer possible. In that case, hit her. But only enough to lightly incapacitate her. Don't become an MMA fighter if she is nowhere near your build or calibre. If she is close to you, but the intent is the same, focus on restraining her. Only hit her in dire situations. If it is only a slight argument and she hits you out of anger, but not enough to severely hurt you, simply restraining her would suffice.
Like you said, if she is going to hit you like a man, she is going to get hit like a man. If she did not want to get hit, she would not have hit others. When you attempt to hit someone, you face the possibility of getting hit in return.
Choose your battles people. Choose your battles wisely.