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Izanami requires that Sasuke and Itachi feel the same physical sensation twice. How exactly is that possible when both are going to be in susanoo for the duration of the fight. Totsuka blade isn't hyped to penetrate anything whereas susanoo is hyped as a stronger defence in comparison. Susanoo also has better feats.Izanami, or a tricky genjutsu, or a sustained clone feint (like the one that caught Madara.)
We don't know if Sasuke's Susano'o can block the Totsuka blade, which is hyped to be a flawless offense.
Clone feints won't work as Sasuke can always manifest ribcage susanoo. He can see chakra with the sharingan so the real Itachi's presence after Sasuke kills his clone will always be with Sasuke.