Hashi/Tobirama>>Itachi/Sasuke>>>>Madara/Izuna>>>>A/B
Hashi or Tobirama can both avoid Itachi/Sasuke's amaterasu
while Madara/Izuna will try to use susano'o to block it but it will
still burn considering Amaterasu can burn chackra
and A/B is fodder compared to this ninjas