MadaraNoKami

"Nine-Tails, you are merely a momentary life, a temporary existence of coalesced energy… energy that once was a single, ultimate form! An unstable force, lacking in intelligence or sapience, you require a guide to show you purpose. That guide is the Uchiha! The tailed beasts are but slaves to those with blessed eyes. Obey!" Madara Uchiha~

The destruction of the Senju clan. Uchiha supermaciy among the world.