I mean come on I know that like 70% of Naruto fans hates sasuke because he's "gay" and "emo" -.- but still u gotta give the guy some credit now that he awaken the EMS I'm pretty sure he can beat the 6 path of pain
Reasons:
1. Amaterasu- ppl keep saying that the fat pain who can absorb ninjutsu can just absorb it now tell me how he can absorb something that can ignite what ever sasuke is focused on. He can kill five of the pain this way but not the shinra tensei guy
2.genjutsu- sasuke can perform 3 types of genjutsu: sharingan genjutsu, susano'O genjutsu, and tsukoyomi which is one of the most powerful genjutsu there is. I read a tread about this a while ago and so guy said "well if one is under a genjutsu how's sasuke gonna deal with the other 5" and I'm like wtf sasuke cast genjutsu from his eyes and did you forget that all 6 pain vision are linked! So if one falls under his genjutsu all of them is DEAD!
3.susano'O- it is the best defense in Naruto right now! The susano'O has a really fast arrow that is really hard to dodge and he can put Amaterasu on the arrow, he has a sword made out of ameterasu and that big ball of Amaterasu in his third hand
4. Kirin- I know it takes a while to prepare but if he can make it and take preta path out Kirin would take out the rest. On the other tread I read about this shinra tensei can counter attack Kirin I personally don't think so. Naruto withstand shinra tensei with like 30 clones behind him so I'm pretty sure Kirin has the power 2 withstand it but IF shinra tensei can deflect it well sasuke can just wait until he uses it then use Kirin in that 5 seconds
So I think if after this you still think sasuke would not have a chance against the 6 path of pain then your just a hater and I'm not saying he can beat nagato just the 6 path and some ppl always says rinegan is stronger than the sharingan so sasuke would always lose
I agree that the rinegan is stronger than the sharingan but if that's ur argument is about eyes then sasuke would have a better chance of beating Pain than naruto cuz last time I check the rinegan is way stronger than regular eyes -.- so ya I'm sure he can beat the 6 path of pain 
Reasons:
1. Amaterasu- ppl keep saying that the fat pain who can absorb ninjutsu can just absorb it now tell me how he can absorb something that can ignite what ever sasuke is focused on. He can kill five of the pain this way but not the shinra tensei guy
2.genjutsu- sasuke can perform 3 types of genjutsu: sharingan genjutsu, susano'O genjutsu, and tsukoyomi which is one of the most powerful genjutsu there is. I read a tread about this a while ago and so guy said "well if one is under a genjutsu how's sasuke gonna deal with the other 5" and I'm like wtf sasuke cast genjutsu from his eyes and did you forget that all 6 pain vision are linked! So if one falls under his genjutsu all of them is DEAD!
3.susano'O- it is the best defense in Naruto right now! The susano'O has a really fast arrow that is really hard to dodge and he can put Amaterasu on the arrow, he has a sword made out of ameterasu and that big ball of Amaterasu in his third hand
4. Kirin- I know it takes a while to prepare but if he can make it and take preta path out Kirin would take out the rest. On the other tread I read about this shinra tensei can counter attack Kirin I personally don't think so. Naruto withstand shinra tensei with like 30 clones behind him so I'm pretty sure Kirin has the power 2 withstand it but IF shinra tensei can deflect it well sasuke can just wait until he uses it then use Kirin in that 5 seconds
So I think if after this you still think sasuke would not have a chance against the 6 path of pain then your just a hater and I'm not saying he can beat nagato just the 6 path and some ppl always says rinegan is stronger than the sharingan so sasuke would always lose