If I wanted to I could compare the lives Tsunade directly saves compared to Jiraiya and Kakashi but I am not going to as they all saved the village in a way. Tsunade didnt stand there and look pretty, she gave all her chakra to the villagers and saved their lives with Katsuyu.Exactly what move did she make other than gritting her teeth and talking tough?Contrast that with what Kakashi and Jiraiya did.Also Asura Path was a weakling and taken out thricee (if I recall,once by Jiraiya,then by Kakashi and then by Naruto) and yet she couldnt defend herself against him
Tsunade was supposed to take Asura out herself but Kishimoto changed it last minute to allow Pain all to Naruto. She could have reacted to it but Naruto was quicker.